What causes Necrotizing Enterocolitis (NEC)? - Tala Talks NICU
NEC is a horrible, horrible disease, that strikes (mostly) premature infants VERY suddenly. Watch this video the answer the following:
WHY is the gut SO different from every other organ in the body?
WHY do we have 100 trillion bacteria hanging out in the intestines?
WHY is the immature gut so susceptible to NEC?
AND
WHAT can we do to prevent NEC?
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Dr. Tala is a board-certified neonatologist, and has worked in busy level III and IV units for the past 15 years. She has won multiple teaching awards throughout her time as a neonatologist.
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References:
Patel et al. Association of Red Blood Cell Transfusion, Anemia, and Necrotizing Enterocolitis in Very Low-Birth-Weight Infants. JAMA 2016 315 (9) 889-897
Clinical Report by American Academy of Pediatrics. Use of Probiotics in Preterm Infants
Pediatrics Volume 147, Number 6, June 2021
Shafir et al. Cochrane Library 2020. Probiotics to prevent necrotizing entercolitis in very preterm low birth weight infants
Quigley et al. Cochrane Library 2019. Formula versus donor breast milk for feeding preterm or low birth weight infants
Darling et al. Controlled Trial of Two Incremental Milk-Feeding Rates in Preterm Infants. N Engl J Med 381;15 October 10 2019
More et al. Association of inhibitors of gastric acid secretion and higher incidence of necrotizing enterocolitis in preterm very low birth weight infants. Am J Perinatol. 2013;30 (10); 849-856
Dasani et al. Standardized feeding regimen for reducing necrotizing enterocolitis in preterm infants: an updated systematic review. J Perinatol. 2017; 37 (7) 827-833
J. Neu and A. Walker. Necrotizing Enterocolitis N. Engl J Med 364;3 January 20 2011
J Neu. Necrotizing Enterocolitis: The Future. Neonatology 2020; 117:240-244
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**Timestamps**
1:11 General Facts about NEC
4:37 General Facts about the gut
12:23 Pathophysiology of NEC
16:11 What can we do to prevent NEC?
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Music: www.bensound.com (royalty free with credit)
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*Disclaimer*: This video is intended for educational purposes only and while
we strive to give the most accurate information, errors may occur. Subsequently,
this video should not be a replacement for medical advice.
