Dr. Lera talks about cancer in dogs.
There are many factors that can influence the development of cancer but, just as in humans, it is impossible to truly know why some individuals develop cancer while others do not. In some cases, exposure to known carcinogens (cancer-causing agents) such as sunlight, chemicals, and cigarette smoke can play a factor. In other cases, especially with certain breeds (Golden Retrievers, Dobermans, German Shepherds, Bernese Mountain Dogs, and Boxers to name a few), there is a genetic susceptibility to cancer. Some cancers are causally linked to obesity, infection, and inflammation, and some need hormones to develop and persist. If cells undergo more and more divisions as the pet ages, the possibility of a mistake (mutation) occurring during these cell divisions increases. The result is that the incidence of cancer increases with age.
The most obvious sign of most cancers is a lump that continues to enlarge. This lump may ulcerate, bleed, or cause other physical effects (e.g., pressure and displacement of the surrounding tissues). Because cancer can develop in any cell in the body, internal cancers can be more difficult to spot. Unexplained, chronic weight loss can be an important sign of cancer. Other signs of cancer can be abnormal bleeding, unexplained vomiting or diarrhea, swollen lymph nodes, coughing, and lameness. Bad breath or a change in eating patterns can be a sign of oral cancer. (source: VCA Hospitals)
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