Seminar Title: Phylomapping: the use of nature’s experiments to understand the genetic regulation of diversity, development and disease
December 15, 2022 - Dr. Matthew Harris gives a presentation on his research, which leverages forward genetic as well as genomic approaches to understand developmental processes that potentiate growth and patterning in late development. His lab’s work combines analysis of mutants identified in zebrafish and comparative genomics in a broad expanse of other fishes exhibiting unique phenotypes. These approaches have proven to be powerful in modeling developmental and genetic causes of both evolutionary change and human skeletal disorders. The Harris Lab has also provided a foundation for the use of fish as experimental models and comparative genomics to understand the genetic regulation of development and disease. Current research program focuses on the regulation of proportional growth, bioelectric regulation of development and regeneration, as well as stem cell maintenance in aging.
Relevant Links:
NHGRI DIR Seminar Series: https://www.genome.gov/event-calendar...
The Harris Laboratory: http://fishbonelab.org/